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cacna2d4

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Official Full Name
calcium channel, voltage-dependent, alpha 2/delta subunit 4
Background
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Synonyms
CACNA2D4; calcium channel, voltage-dependent, alpha 2/delta subunit 4; voltage-dependent calcium channel subunit alpha-2/delta-4; voltage-gated calcium channel alpha(2)delta-4 subunit; voltage-gated calcium channel subunit alpha-2/delta-4; RCD4; RCD4,CACNA2D4