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cacna1e

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Official Full Name
calcium channel, voltage-dependent, R type, alpha 1E subunit
Background
This gene encodes an integral membrane protein that belongs to the calcium channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing. [provided by RefSeq, Jul 2008]
Synonyms
CACNA1E; calcium channel, voltage-dependent, R type, alpha 1E subunit; BII; Cach6; Cav2.3; Cchra1; alpha1E; Cacnl1a6; A430040I15; voltage-dependent R-type calcium channel subunit alpha-1E; brain calcium channel II; voltage-gated calcium channel subunit alpha Cav2.3; calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit

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