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c1galt1

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Official Full Name
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
Background
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.
Synonyms
C1GALT1; core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; C1GALT; core 1 beta3 Gal T; T synthase; B3Gal-T8; core 1 beta3-Gal-T1; core 1 O-glycan T-synth; core 1 O-glycan T-synthase; core 1 beta1,3-galactosyltransferase 1; core1

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