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btg1

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Official Full Name
B-cell translocation gene 1, anti-proliferative
Background
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
Synonyms
BTG1; B-cell translocation gene 1, anti-proliferative; protein BTG1; B-cell translocation gene 1 protein; B-cell translocation gene 1; btg-a; sb:cb1010; zgc:65815; wu:fb14h05; wu:fb40c11; wu:fk92d10