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Official Full Name
pleckstrin homology domain interacting protein
Background
PHIP binds the pleckstrin homology (PH) domain of insulin receptor substrate-1 (IRS1; MIM 147545), modulates insulin;signaling, and plays a role in pancreatic beta cell growth and survival (Farhang-Fallah et al., 2000 (PubMed;11018022); Podcheko et al., 2007 (PubMed 17636024)).
Synonyms
PHIP; pleckstrin homology domain interacting protein; WDR11; PH-interacting protein; BRWD2; DCAF14; DDB1 and CUL4 associated factor 14; FLJ20705; ndrp; IRS-1 PH domain-binding protein; WD repeat-containing protein 11; FLJ45918; MGC90216