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brip1

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Official Full Name
BRCA1 interacting protein C-terminal helicase 1
Background
Fanconi anemia group J protein is a protein that in humans is encoded by the BRCA1-interacting protein 1 (BRIP1) gene. The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. This protein also appears to be important in ovarian cancer where it seems to act as an antioncogene
Synonyms
BRIP1; BRCA1 interacting protein C-terminal helicase 1; OF; BACH1; FANCJ; Fanconi anemia group J protein; ATP-dependent RNA helicase BRIP1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein; BRCA1-interacting protein C-terminal helicase 1; FLJ90232; MGC126521; MGC126523; BRCA1-interacting protein 1; BRCA1/BRCA2 associated helicase 1; BRCA1-binding helicase-like protein BACH1; Fanconi anemia group J protein homolog; si:ch211-158l18.1; Fanconi anemia J; complementation group J