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boll

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Official Full Name
Homo sapiens bol, boule-like (Drosophila) DNA.
Background
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms
BOLL; bol, boule-like (Drosophila); bol (Drosophila boule homolog) like; protein boule-like; BOULE

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