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Official Full Name
Bloom syndrome, RecQ helicase-like
Background
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3-5 helicase activity.The normal protein may act to suppress inappropriate recombination.
Synonyms
BLM; Bloom syndrome, RecQ helicase-like; Bloom syndrome; Bloom syndrome protein; BS; RECQ2; RECQL3; recQ protein-like 3; DNA helicase, RecQ-like type 2; RECQL2; MGC126616; MGC131618; MGC131620; ORF1; Bloom syndrome protein homolog; Gd BLM; BLM helicase; recQ helicase homolog

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