Official Full Name
baculoviral IAP repeat containing 3
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF4; RNF49; TNFR2 TRAF signaling complex protein; IAP-1; IAP homolog C; RING finger protein 49; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; AIP1; API2; HAIP1; HIAP1; c-IAP2