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bclaf1

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Official Full Name
BCL2-associated transcription factor 1
Background
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
BCLAF1; BCL2-associated transcription factor 1; bcl-2-associated transcription factor 1; BTF; KIAA0164; bK211L9.1