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bcap29

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Official Full Name
B-cell receptor-associated protein 29
Background
BAP29 and the related protein BAP31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both BAP29 and BAP31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the BAP29/BAP31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that BAP29 and BAP31 may act as chaperones for transmembrane regions of various proteins. There are multiple isoforms of BAP29.
Synonyms
BCAP29; B-cell receptor-associated protein 29; BAP29; FLJ53907; DKFZp686M2086; BCR-associated protein 29; OTTHUMP00000206633; OTTHUMP00000206634; OTTHUMP00000206639; OTTHUMP00000214583; OTTHUMP00000214584; OTTHUMP00000214585; OTTHUMP00000214586; BAP29, DKFZp686M2086, FLJ53907, BCAP29; B-cell receptor-associated protein BAP29; zgc:110731; si:dkey-217k21.7