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bank1

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Official Full Name
B-cell scaffold protein with ankyrin repeats 1
Background
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Synonyms
BANK1; B-cell scaffold protein with ankyrin repeats 1; B-cell scaffold protein with ankyrin repeats; BANK; FLJ20706; FLJ34204