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b2m

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Official Full Name
beta-2-microglobulin
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Synonyms
B2M; beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; beta-2 microglobulin; bwm; wu:fa94c05; wu:fb10a09

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