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avpr1b

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Official Full Name
arginine vasopressin receptor 1B
Background
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Synonyms
AVPR1B; arginine vasopressin receptor 1B; AVPR3; vasopressin V1b receptor; Antidiuretic hormone receptor 1B; AVPR V1b; AVPR V3; V1bR; V1BR_HUMAN; Vasopressin V3 receptor; VPR3; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; pituitary vasotocin receptor; si:ch211-125a15.3; V1A(1); avtr1a1; arginine vasotocin receptor 1a1