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atp5c1

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Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14.
Synonyms
ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; ATP5C, ATP5CL1; ATP synthase subunit gamma, mitochondrial; ATP synthase gamma chain, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma subunit; ATP5C 1; ATP5C; ATP5CL1; F ATPase gamma subunit; Mitochondrial ATP synthase, gamma subunit 1; F-ATPase gamma subunit; zgc:73209; wu:fk34c05

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