Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.<br/>May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); APG5 (autophagy 5, S. cerevisiae) like , APG5 autophagy 5 like (S. cerevisiae) , APG5L; apoptosis specific protein; ASP, APG5, APG5L, hAPG5, APG5-LIKE; zgc:100934; autophagy 5-like protein