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atg10

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Official Full Name
autophagy related 10
Background
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
Synonyms
ATG10; autophagy related 10; APG10; APG10L; pp12616; ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog; ATG10 autophagy related 10 homolog (S. cerevisiae); APG10 autophagy 10 like (S. cerevisiae) , APG10L; DKFZP586I0418; FLJ13954; APG10, APG10L, pp12616; im:7153729; zgc:123341