ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2.
ART1; ADP-ribosyltransferase 1; GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; ART2; CD296; ADP ribosyltransferase 1; ADP ribosyltransferase 2; ART 1; CD296 antigen; GPI linked NAD(P)(+) arginine ADP ribosyltransferase 1; MGC133217; Mono(ADP ribosyl)transferase; RT6; ADP-ribosyltransferase 2; mono(ADP-ribosyl)transferase 1; ART7.1; GPI-anchored ADP-ribosyltransferase; ARTC1