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arhgap22

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Official Full Name
Rho GTPase activating protein 22
Background
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS;superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt;and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of;these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been;found for this gene.
Synonyms
ARHGAP22; Rho GTPase activating protein 22; rho GTPase-activating protein 22; RhoGAP2; Rho GTPase activating protein 2; rho-type GTPase-activating protein 22; RhoGap22