Official Full Name
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are;cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific;ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during;development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein;apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced;transcript variants encoding multiple isoforms have been observed for this gene.
LRP8; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; low-density lipoprotein receptor-related protein 8; APOER2; ApoE receptor 2; MCI1; LRP-8; HSZ75190; LR8B; apolipoprotein E receptor 2