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aoc2

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Official Full Name
amine oxidase, copper containing 2
Background
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
Synonyms
AOC2; amine oxidase, copper containing 2 (retina-specific); retina-specific copper amine oxidase; DAO2; RAO; Amine oxidase [copper containing]; Amine oxidase copper containing 2 (retina specific); Amine oxidase copper containing 2; Retina specific copper amine oxidase; SSAO; semicarbazide-sensitive amine oxidase; amine oxidase, copper containing 2; aoc3; wu:fa94a08; wu:fe14c05; zgc:113006; fa94a08; fe14c05; amine oxidase, copper containing 3