The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some;of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a;phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in;cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental;anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin;CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein;product with a molecular weight of about 35 kDa.
ANXA5; annexin A5; ANX5, ENX2; CBP-I; PAP-I; VAC-alpha; annexin V; annexin-5; anchorin CII; endonexin II; lipocortin V; calphobindin I; thromboplastin inhibitor; vascular anticoagulant-alpha; placental anticoagulant protein 4; placental anticoagulant prot; placental anticoagulant protein I; PP4; ANX5; ENX2