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anapc7

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Official Full Name
anaphase promoting complex subunit 7
Background
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Synonyms
ANAPC7; anaphase promoting complex subunit 7; APC7; anaphase-promoting complex subunit 7; cyclosome subunit 7; si:ch211-127h20.1

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