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anapc4

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Official Full Name
anaphase promoting complex subunit 4
Background
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known.
Synonyms
ANAPC4; anaphase promoting complex subunit 4; anaphase-promoting complex subunit 4; APC4; ANAPC 4; APC 4; APC Complex Protein CUT20; APC4_HUMAN; CUT20; Cyclosome subunit 4; LID1; OTTHUMP00000123382; OTTHUMP00000218479; zgc:101872; si:dkey-90m5.2

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