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alk-7

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Official Full Name
activin A receptor, type IC
Background
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Synonyms
ACVR1C; activin A receptor, type IC; ALK7; ACVRLK7; activin receptor type-1C; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7