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akt2

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Official Full Name
v-akt murine thymoma viral oncogene homolog 2
Background
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Synonyms
Akt2; AKT2_HUMAN; PKB; PKB beta; PKBBETA; PRKBBy; Protein kinase Akt 2; Protein kinase Akt-2; Protein kinase B beta; RAC BETA; RAC beta serine threonine protein kinase; RAC PK beta; Rac protein kinase beta; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; RACbeta; V AKT Murine Thymoma Viral Oncogene Homolog 2; v-akt murine thymoma viral oncogene homolog 2; murine thymoma viral (v-akt) homolog-2; PKBB; PRKBB; HIHGHH; RAC-BETA; cb945