Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER

ak2

Bookmark and Share
Official Full Name
adenylate kinase 2
Background
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the;reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2,;and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is;tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may;play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in;multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Synonyms
AK2; adenylate kinase 2; adenylate kinase 2, mitochondrial; ATP-AMP transphosphorylase 2; adenylate kinase isoenzyme 2, mitochondrial; ADK2; AK 2; ADK2, AK 2,AK2; wu:fb34f05; wu:fj80e03