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aga

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Official Full Name
aspartylglucosaminidase
Background
Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified.
Synonyms
AGA; aspartylglucosaminidase; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; ASRG; glycosylasparaginase; AGU; Aspartylglucosylamine deaspartylase; Aspartylglycosaminuria; ASPG_HUMAN; GA; Glycosylasparaginase beta chain; N4 (N acetyl beta glucosaminyl) L asparagine amidase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase; zgc:77327