This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5 UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ADH6; alcohol dehydrogenase 6 (class V); alcohol dehydrogenase 6; ADH 5; ADH 6; Aldehyde reductase; Class V alcohol dehydrogenase 6; UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL; OTTHUMP00000161647; OTTHUMP00000161648; OTTHUMP00000161649; OTTHUMP00000220107; ADH-5; ADH1A; ADH1B; beta subunit; beta polypeptide; alpha polypeptide; alcohol dehydrogenase ADH-F; class I alcohol dehydrogenase; alcohol dehydrogenase 1B (class I), beta polypeptide; alcohol de