This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide; ADH3; alcohol dehydrogenase 1C; Alcohol dehydrogenase 3; Class I alcohol dehydrogenase; ADH gamma subunit; ADH1G_HUMAN; Alcohol dehydrogenase 1C (class I) gamma polypeptide; Alcohol dehydrogenase 1C gamma polypeptide; Alcohol dehydrogenase 3 (class I) gamma polypeptide; Alcohol dehydrogenase subunit gamma; Aldehyde reductase; OTTHUMP00000220209; ADH, gamma subunit; alcohol dehydrogenase 3 (class I), gamma polypeptide; ADH3,ADH1C