This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma.
ADAM7; ADAM metallopeptidase domain 7; a disintegrin and metalloproteinase domain 7; disintegrin and metalloproteinase domain-containing protein 7; EAPI; GP 83; Sperm maturation related glycoprotein GP83; epididymal apical protein I; sperm maturation-related glycoprotein GP-83; GP83; GP-83; ADAM 7; ADAM-7; ADAM 7, ADAM-7, EAPI, GP-83, GP83,ADAM7