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actr1a

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Official Full Name
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
Background
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size;from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of;cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle;formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per;dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is;approximately 60% identical at the amino acid level to conventional actin.
Synonyms
ACTR1A; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1 (actin related protein 1, yeast) homolog A (centractin alpha); alpha-centractin; ARP1; actin related protein 1; Actin RPV; ACTR 1A; Alpha Centractin; ARP 1; ARP1 actin related protein 1 homolog A; ARP1 actin related protein 1 homolog A centractin alpha; ARP1 yeast homolog A; Centractin alpha; Centractin; Centrosome associated actin homolog; CTRN 1; CTRN1; FLJ52695; FLJ52800; FLJ55002; actin-RPV; centrosome-associated actin homolog; ARP1, CTRN1, FLJ52695, FLJ52800, FLJ55002, ACTR1A

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