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acsl6

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Official Full Name
acyl-CoA synthetase long-chain family member 6
Background
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms
ACSL6; acyl-CoA synthetase long-chain family member 6; FACL6, fatty acid Coenzyme A ligase, long chain 6; long-chain-fatty-acid--CoA ligase 6; ACS2; KIAA0837; LACS2; LACS5; long fatty acyl-CoA synthetase 2; fatty-acid-Coenzyme A ligase, long-chain 6; FAC; FACL6; LACS 6; FLJ16173

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