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acox2

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Official Full Name
acyl-CoA oxidase 2, branched chain
Background
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children.
Synonyms
ACOX2; acyl-CoA oxidase 2, branched chain; acyl Coenzyme A oxidase 2, branched chain; peroxisomal acyl-coenzyme A oxidase 2; BRCACOX; BRCOX; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase; ACOX 2; Acyl Coenzyme A oxidase 2; Acyl Coenzyme A oxidase 2 branched chain; Acyl coenzyme A oxidase 2 peroxisomal; BCOX; Peroxisomal branched chain acyl CoA oxidase; THCA CoA oxidase; THCCox; Trihydroxycoprostanoyl CoA oxidase; THCA-CoA oxidase; OTTHUMP00000214196; OTTHUMP00000214197; trihydroxycoprostanoyl-CoA oxidase; acyl-Coenzyme A oxidase 2, branched chain; peroxisomal branched chain acyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-bet; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; BCOX, BRCOX, THCCox, BRCACOX; THCA

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