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abr

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Official Full Name
active BCR-related
Background
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.
Synonyms
ABR; active BCR-related gene; active breakpoint cluster region-related protein; MDB; Active BCR related gene; Active breakpoint cluster region related protein