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The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), has infected millions of people worldwide. Coronavirus is highly infectious and able to spread rapidly among the population through close contact and respiratory droplets. Therefore, effective personal protection is critically important to prevent the spread of SARS-CoV-2.
In SARS-CoV-2 infection, the spike (S) protein of SARS-CoV-2 binds to host cell receptor angiotensin-converting enzyme 2 (ACE2) which mediates viral entry. The extracellular region of ACE2 contains two domains. One of them is zinc metallopeptidase domain that can be further divided into two subdomains, forming a deep channel at the top of ACE2 molecules. The surface of the deep channel and the surrounding ridges are negatively charged which provide a possible binding site for positively charged receptor-binding domain (RBD) of the S protein.
Recent studies reported that cells in the upper respiratory tract are likely the coronavirus' initial and major site of entry into the body. Therefore, nasal and oral mucosa should be thoroughly protected against viral infection. Nasally prophylactic approaches or administered therapeutics may have great potentials to effectively and precisely prevent the transmission of the coronavirus in people.
Creative Biogene provides the medical antiviral antibacterial liquid dressing, which can build a negatively charged defensive wall on the surface of mucosal cells to effectively prevent the viral and bacterial infection.
- Sodium Hyaluronate, a natural linear anionic polysaccharide, can balance the surrounding positive and negative ions and inhibit the activity of multiple enzymes. Sodium Hyaluronate with various molecular weights forms three-dimensional network structures via cross-linking with each other to filter viruses and bacteria. It can also penetrate and reach the deeper skin layers which has many benefits for skin care.
- Chitosan is a natural antimicrobial polymer agent. Chitosan has multiple advantages including its outstanding biocompatibility, nontoxicity, broad-spectrum antibacterial properties, anti-viral and anti-fungal activities. It also possesses multiple therapeutic effects, such as hemostasis, pain relief, reducing inflammation, repairing mucous membrane, and accelerating wound healing.
- Honeysuckle and chrysanthemum extracts: natural agents, have anti-bacterial, anti-inflammatory and immune-regulatory properties. Honeysuckle extract has the ability to inhibit the protein synthesis of drug-resistant bacteria, and thus is applied for protection against respiratory tract infections including pneumonia, as well as other viral and bacterial infections.
- Peppermint extract: potent antiviral and analgesic substance.
If you are interested in our medical antiviral antibacterial liquid dressing product, please contact us today to get more information. Our scientists would be happy to answer your questions. We look forward to hearing from you. Contact us today at firstname.lastname@example.org for support.