shRNA set against Human NTRK2(NM_001018064.1)

Cat.No.

SHR008868

Description

Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.

Content

Each set contains 4 shRNA expression constructs.

Format

5 μg purified plasmid

Promoter

Report Gene

eGFP

Selection Marker

Puromycin

Species

Human

Unit Size

5 μg

Gene Information

Gene Name

NTRK2 neurotrophic tyrosine kinase, receptor, type 2 [ Homo sapiens ]

Gene Symbol

NTRK2

Synonyms

TRKB; trk-B; GP145-TrkB

Gene Description

neurotrophic tyrosine kinase, receptor, type 2

Gene ID

4915

UniProt ID

Q16620

mRNA Refseq

NM_006180.3

Protein Refseq

NP_006171.2

Chromosome Location

9q22.1

Function

ATP binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor-activated receptor activity; neurotrophin binding; neurotrophin binding; protein homodimerization activity;

Pathway

Activation of TRKA receptors, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; NGF-independant TRKA activation, organism-specific biosystem;

MIM

600456

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shRNA set against Human NTRK2(NM_001018064.1) (SHR008868)

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