Tel: 1-631-626-9181 (USA)   44-208-144-6005(Europe)
  Email:

TNFRSF11B

Official Full Name
tumor necrosis factor receptor superfamily, member 11b
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG; TR1; OCIF; tumor necrosis factor receptor superfamily member 11B; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG, osteoprotegerin; MGC29565; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

Interested in learning more?

Contact us today for a free consultation with the scientific team and discover how Creative Biogene can be a valuable resource and partner for your organization.

Request a quote today!