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TBP

Official Full Name
TATA box binding protein
Background
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Synonyms
GTF2D,GTF2D1,HDL4,MGC117320,MGC126054,MGC126055,SCA17,TATA binding factor,TATA box factor,TATA sequence binding protein,TATA sequence-binding protein,TATA-binding factor,TATA-box binding protein N-terminal domain,TATA-box factor,TATA-box-binding protein,TBP,TBP_HUMAN,TFIID,Transcription initiation factor TFIID TBP subunit; TATA; binding protein TBP; TBP; TATA box binding protein; GTF2D1, SCA17; TATA-box-binding protein; TFIID; TATA-box factor; TATA sequence-binding protein; TATA-box binding protein N-terminal domain; transcription initiation factor TFIID TBP subunit; HDL4; GTF2D; SCA17; GTF2D1; MGC117320; MGC126054; MGC126055; TBP1; TATA-binding factor; TATA-binding protein; TA-TA binding protein 1; fd20h06; zgc:66213; wu:fd20h06; si:zc101n13.2

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