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CYP1B1

Official Full Name
cytochrome P450, family 1, subfamily B, polypeptide 1
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
Synonyms
CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1; CP1B; GLC3A; CYPIB1; P4501B1; cytochrome P450 1B1; microsomal monooxygenase; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); cytochrome P450, subfamily I (dioxin inducible), polypeptide 1 (glaucoma 3, primary infantile) , GLC3A; CP1B, GLC3A, CYPIB1, P4501B1; CYP1B; zgc:136223; cytochrome P4501B

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