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Cnr2

Official Full Name
cannabinoid receptor 2 (macrophage)
Background
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
Synonyms
CNR2; cannabinoid receptor 2 (macrophage); CB2; CX5; CB-2; cannabinoid receptor 2; testis-dominant CNR2 isoform CB2; cb2a; cb2b; CB2R; cannabinoid receptor 2 type A; cannabinoid receptor-like cb2-zf

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