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Dnaic2


Official Full Name
dynein axonemal intermediate chain 2
Organism
Mus musculus
Gene ID
432611
Background
Predicted to enable dynein heavy chain binding activity; dynein light chain binding activity; and microtubule motor activity. Predicted to be involved in cilium movement and outer dynein arm assembly. Predicted to act upstream of or within cilium assembly and determination of left/right symmetry. Located in several cellular components, including axoneme; external side of plasma membrane; and glial cell projection. Is expressed in spermatozoon and testis. Used to study Kartagener syndrome and primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 9. Orthologous to human DNAI2 (dynein axonemal intermediate chain 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Dnai2; Gm728; Dnaic2; b2b3405Clo; C030015H18Rik

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