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Cdc2a


Official Full Name
cyclin dependent kinase 1
Organism
Mus musculus
Gene ID
12534
Background
Enables Hsp70 protein binding activity; chromatin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within several processes, including fibroblast proliferation; mitotic G2 DNA damage checkpoint signaling; and mitotic cell cycle phase transition. Part of cyclin A2-CDK1 complex. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Orthologous to human CDK1 (cyclin dependent kinase 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Cdk1; Cdc2; Cdc2a; p34<CDC2>

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