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VPRBP

Official Full Name
DDB1 and CUL4 associated factor 1
Organism
Homo sapiens
GeneID
9730
Background
Enables histone H2AT120 kinase activity; nuclear estrogen receptor binding activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including cell competition in a multicellular organism; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of primary metabolic process. Located in COP9 signalosome; fibrillar center; and nucleoplasm. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in centrosome. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
DCAF1; RIP; VPRBP;

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