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USP35


Official Full Name
ubiquitin specific peptidase 35
Organism
Homo sapiens
Gene ID
57558
Background
This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues. [provided by RefSeq, Jul 2017]
Synonyms
Zfp800; Znf800

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SHH441529 shRNA set against Human USP35 (NM_020798.2) Inquiry
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CDCH098772 Mouse Usp35 ORF clone (NM_001177412.1) Inquiry
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