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TAB3


Official Full Name
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Organism
Homo sapiens
Gene ID
257397
Background
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
NAP1; MAP3K7IP3

Cat.No. Product Name Price
SHH422372 shRNA set against Human TAB3 (NM_152787.3) Inquiry
SHH422376 shRNA set against Mouse TAB3 (NM_025729.4) Inquiry
SHW010035 shRNA set against Danio rerio TAB3 (NM_001045105) Inquiry
Cat.No. Product Name Price
MiUTR1H-06068 TAB3 miRNA 3'UTR clone Inquiry
MiUTR1M-06922 TAB3 miRNA 3'UTR clone Inquiry
CDCB171510 Danio rerio TAB3 ORF Clone (NM_001045105) Inquiry
CDCB193832 Rabbit TAB3 ORF clone (XM_002720010.2) Inquiry
CDCL150310 Human TAB3 ORF clone (NM_152787.3) Inquiry
CDCR257534 Mouse Tab3 ORF Clone(NM_025729.4) Inquiry
CDCS419693 Human TAB3 ORF Clone (BC032526) Inquiry
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