Official Full Name

phosphatidic acid phosphatase type 2C

Background

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Synonyms

PPAP2C; phosphatidic acid phosphatase type 2C; lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; EC 3.1.3.4; PAP2 G; PAP2 gamma; PAP2c; PAP2G; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; Phosphatidic acid phosphohydrolase type 2c; Type 2 phosphatidic acid phosphatase gamma; PAP2-gamma; type-2 phosphatidic acid phosphatase-gamma; PAP-2c; PAP2-g