Pages
Products

PDCD6IP


Official Full Name
programmed cell death 6 interacting protein
Organism
Homo sapiens
Gene ID
10015
Background
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
Synonyms
AIP1; ALIX; HP95; DRIP4; MCPH29

Cat.No. Product Name Price
SHH372248 shRNA set against Human PDCD6IP (NM_013374.5) Inquiry
SHH372252 shRNA set against Mouse PDCD6IP (NM_011052.2) Inquiry
SHH372256 shRNA set against Rat PDCD6IP (NM_001029910.2) Inquiry
SHW001618 shRNA set against Chicken PDCD6IP (NM_001030993) Inquiry
SHW018426 shRNA set against Danio rerio PDCD6IP (NM_213360) Inquiry
Cat.No. Product Name Price
CDCH018357 Mouse PDCD6IP ORF clone(NM_011052.2) Inquiry
CDCS408709 Human PDCD6IP ORF Clone (BC020066) Inquiry
CDFR004127 Rat Pdcd6ip cDNA Clone(NM_001029910.2) Inquiry
CDCB163093 Chicken PDCD6IP ORF Clone (NM_001030993) Inquiry
CDCB179901 Danio rerio PDCD6IP ORF Clone (NM_213360) Inquiry
CDCB192735 Rabbit PDCD6IP ORF clone (XM_008266117.1) Inquiry
CDCL147247 Human PDCD6IP ORF clone (NM_001256192.1) Inquiry
CDCL151598 Mouse Pdcd6ip ORF clone (NM_001164677.1) Inquiry
CDCR240762 Mouse Pdcd6ip ORF Clone(NM_001164678.1) Inquiry
CDCR354191 Human PDCD6IP ORF Clone(NM_001162429.2) Inquiry
CDCR371155 Rat Pdcd6ip ORF Clone(NM_001029910.2) Inquiry
CDCS408710 Human PDCD6IP ORF Clone (BC068454) Inquiry
Quick Inquiry