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Nr2e3

Official Full Name
nuclear receptor subfamily 2, group E, member 3
Background
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms
NR2E3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; rd7; RP37; ESCS; MGC49976; NR2 E3; Nuclear receptor subfamily 2 group E member 3; Photoreceptor specific nuclear receptor; Rd 7; Retina specific nuclear receptor; Retinal degeneration 7; RNR; retina-specific nuclear receptor; photoreceptor cell-specific nuclear receptor variant 1; wu:fj55b07; zgc:103631; NR2D2; fj55b07

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