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NUDT1

Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 1
Background
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.
Synonyms
NUDT1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; MTH1; 7,8-dihydro-8-oxoguanine triphosphatase; 7; 8 dihydro 8 oxoguanine triphosphatase; 8 oxo 7; 8 dihydrodeoxyguanosine triphosphatase; 8 dihydroguanosine triphosphatase; 8 oxo dGTPase; mutT human homolog 1; nucleoside diphosphate linked moiety X type motif 1; nudix motif 1; 8-oxo-dGTPase; 2-hydroxy-dATP diphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; zgc:56560; wu:fb40g09

Cat.No. Product Name Price
CLKO-0551NUDT1 KO Cell Lysate-HEK293TInquiry
Cat.No. Product Name Price
CDCB161728Chicken NUDT1 ORF Clone (NM_001006160)Inquiry
CDCB179951Danio rerio NUDT1 ORF Clone (NM_213418)Inquiry
CDCB188806Rabbit NUDT1 ORF clone (XM_008252638.1)Inquiry
CDCL140517Human Nudt1 ORF clone (NM_008637.1)Inquiry
CDCR283208Human NUDT1 ORF Clone(NM_002452.3)Inquiry
CDCR326394Human NUDT1 ORF Clone(NM_198948.1)Inquiry
CDCR326396Human NUDT1 ORF Clone(NM_198949.1)Inquiry
CDCR326398Human NUDT1 ORF Clone(NM_198950.1)Inquiry
CDCR326402Human NUDT1 ORF Clone(NM_198952.1)Inquiry
CDCR326405Human NUDT1 ORF Clone(NM_198953.1)Inquiry
CDCR326407Human NUDT1 ORF Clone(NM_198954.1)Inquiry
CDCR380764Rat Nudt1 ORF Clone(NM_057120.1)Inquiry
CDCS410804Human NUDT1 ORF Clone (BC014618)Inquiry
CDCS410805Human NUDT1 ORF Clone (BC051375)Inquiry
CDFG012988Human NUDT1 cDNA Clone(NM_198949.1)Inquiry
CDFG012989Human NUDT1 cDNA Clone(NM_198948.1)Inquiry
CDFG012991Human NUDT1 cDNA Clone(NM_198950.1)Inquiry
CDFG012992Human NUDT1 cDNA Clone(NM_198953.1)Inquiry
CDFG012994Human NUDT1 cDNA Clone(NM_198952.1)Inquiry
CDFG012996Human NUDT1 cDNA Clone(NM_198954.1)Inquiry
CDFH012960Human NUDT1 cDNA Clone(NM_002452.3)Inquiry
CDFR013731Rat Nudt1 cDNA Clone(NM_057120.1)Inquiry
MiUTR1H-06962NUDT1 miRNA 3'UTR cloneInquiry
MiUTR1H-06963NUDT1 miRNA 3'UTR cloneInquiry
MiUTR1M-07871NUDT1 miRNA 3'UTR cloneInquiry
MiUTR1R-04317NUDT1 miRNA 3'UTR cloneInquiry
MiUTR3H-03260NUDT1 miRNA 3'UTR cloneInquiry
MiUTR3H-03262NUDT1 miRNA 3'UTR cloneInquiry
MiUTR3H-03263NUDT1 miRNA 3'UTR cloneInquiry
MiUTR3H-03264NUDT1 miRNA 3'UTR cloneInquiry
MiUTR3H-03265NUDT1 miRNA 3'UTR cloneInquiry

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